T5224, RSPO2 and AZD5363 are novel drugs against functional pituitary adenoma
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چکیده
منابع مشابه
Refractory pituitary adenoma: a novel classification for pituitary tumors
Pituitary adenomas are classified as typical or atypical, invasive or noninvasive, and aggressive or nonaggressive based on pathological features, radiological findings, and clinical behavior. Only pituitary tumors with cerebrospinal and/or systemic metastasis are considered malignant carcinomas. However, some pituitary adenomas with high Ki-67 indexes exhibit aggressive behaviors, such as rapi...
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A case of a pituitary adenoma associated with hyperprolactinemia and contiguous to a supra and retrosellar cyst is presented. Only three patients with pituitary adenomas accompanied by parasellar cysts have been previously described. It is the first time that this relationship is illustrated by Magnetic Resonance Imaging (MRI). Simultaneous occurrence of arachnoid cysts and adenomas is generall...
متن کاملHydrocephalus complicating pituitary adenoma.
Hydrocephalus complicated the clinical course of four patients with pituitary adenoma. In three it was noted late, long after surgical intervention and radiotherapy had been carried out. In one patient, hydrocephalus was part of the presenting syndrome. The differential diagnosis of hypopituitarism and occult hydrocephalus is difficult. The possibility of hydrocephalus complicating a pituitary ...
متن کاملMicroRNAs-based network: a novel therapeutic agent in pituitary adenoma.
Pituitary adenomas are common benign intracranial neoplasms representing about 10-25% of all intracranial neoplasm. Significant morbidity can occur along with pituitary adenomas due to hormonal dysfunction and mass effects. The pathogenesis of pituitary adenoma is unclear, however, etiologic factors include genetic events, hormonal stimulation, and growth factors [1], all of which promote cell ...
متن کاملPituitary Adenoma Segmentation
Sellar tumors are approximately 10-15% among all intracranial neoplasms. The most common sellar lesion is the pituitary adenoma. Manual segmentation is a time-consuming process that can be shortened by using adequate algorithms. In this contribution, we present a segmentation method for pituitary adenoma. The method is based on an algorithm we developed recently in previous work where the novel...
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ژورنال
عنوان ژورنال: Aging
سال: 2019
ISSN: 1945-4589
DOI: 10.18632/aging.102372